Health Mythbusters: Red 40 Edition

By: Mallory Mireles


Red 40 is the most widely used dye found in many processed foods and beverages, frequently used in order to enrich the visual appeal of various food items. Approved for use in the United States since In the United States since 1971, Red 40, alongside eight other artificial food dyes, has encountered significant inspection and raised concerns among consumers regarding its safety and potential health effects.

What is Red 40?

Red 40, also known as Allura Red AC, is a synthetic food dye derived from petroleum. It’s widely used in the food industry to impart a vibrant red color to various products, including breakfast cereals, candies, beverages, snacks, baked goods, vitamins, and even some medications. Despite its approval by regulatory agencies like the FDA, which conducted a review of the dye as recently as 2019, Red 40’s safety remains a topic of debate. Notably, the European Union mandates warning notices on most artificially dyed products, signaling growing international concern about its usage.

Red 40 and Nutrition:

The primary purpose of Red 40 is to create distinct and uniform colors of consumable products that would otherwise be colorless. Products containing Red 40 typically provide little to no nutritional value. They are often loaded with artificial ingredients and additives, offering empty calories and no essential nutrients. A notable underscores the differences between Fanta orange soda in the United Kingdom, colored with natural extracts like pumpkin and carrot, while the United States uses Red 40 and Yellow 6. It’s essential to be mindful of consuming such products regularly, as they contribute to a diet high in processed foods and low in nutritional quality.

Health Effects of Red 40:

Research on the debates surrounding Red 40 is inconclusive and often conflicting. Some studies suggest potential links between Red 40 consumption and adverse health outcomes, while others find no significant associations. Here are some conclusions of Red 40 studies: 

  • Behavioral Effects: Certain studies have raised concerns about the impact of artificial food dyes, including Red 40, on children’s behavior. For instance, a double-blinded randomized trial conducted by McCann et al. investigated the effects of food additives on hyperactive behavior in children, suggesting a potential link between food dyes and hyperactivity in sensitive individuals. However, more robust evidence is needed to establish causation definitively.
  • Allergic Reactions: Like other food additives, Red 40 may trigger allergic reactions of hypersensitivity in some individuals, as demonstrated in a study by Weisbrod et al. The study found that color additives in Slurpee beverages elicited such reactions. Symptoms can range from mild to severe and may include skin rashes, itching, gastrointestinal discomfort, and respiratory issues. If you suspect an allergy to Red 40 or any other food dye, it’s essential to seek medical advice and consider avoiding products containing these additives. 
  • Cancer Risk: Concerns have been raised regarding the potential carcinogenicity of Red 40 and other synthetic food dyes. Studies, such as the research conducted by Kobylewski and Jacobson in their study “Toxicology of Food Dyes,” have suggested a possible link between food dyes and cancer risk, with Red 40 found to be contaminated with benzidine and other carcinogens. However, evidence in humans is limited and inconclusive. Regulatory agencies like the FDA have deemed Red 40 safe for consumption based on current available data, but ongoing research is warranted to assess long-term health effects fully.


Red 40 raises questions about its safety and potential health effects. While it is widely used as a food additive and approved for consumption by regulatory authorities, concerns persist regarding its impact on health, particularly in sensitive individuals and children. As with any food or beverage ingredient, moderation and awareness are key for a healthy lifestyle.

When it comes to making dietary choices, prioritizing whole, minimally processed foods is generally advisable. Given that Red 40 provides no known nutritional or physical benefits, it is crucial to minimize consumption of products containing this additive whenever possible. Research has consistently shown that processed food containing artificial dyes like Red 40 contribute to a diet high in sugar, unhealthy fats, and sodium, while lacking essential vitamins and minerals. Opting for natural sources of color and flavor, such as fruits and vegetables, can help reduce reliance on artificial additives like Red 40. Ultimately, staying informed, reading labels, and making conscious decisions about what we consume can contribute to overall health and well-being.